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American Ginseng

American Ginseng (Panax quinquefolium) is a species of Ginseng native to North America.  It contains similar active constituents to Korean Ginseng.

American Ginseng is used for the treatment of these conditons:

Alzheimer’s Disease:

A laboratory study fuond that constituents of American ginseng stimulate the brain receptors (named nicotinic receptors) that are most affected during the course of Alzheimer’s disease.

This stimulation of nicotinic receptors may temporarily improve cognitive function in Alzheimer’s disease patients.

Attention Deficit Disorder:

A clinical study tested American ginseng (combined with Ginkgo biloba) in childran aged 3 – 17 with ADD.  During the study, parents of ADD children filled in a questionnaire that assesses a broad range of problem behaviours (and was used as an indication of ADD symptom severity).  After 2 weeks of treatment, the proportion of the subjects exhibiting improvement ranged from 31% for the anxious-shy attribute to 67% for the psychosomatic attribute.  After 4 weeks of treatment, the proportion of subjects exhibiting improvement ranged from 44% for the social problems attribute to 74% for the overall ADD index.

Diabetes Type 2:

Two clinical studies have shown that American ginseng taken before or during a meal lowers blood sugar levels in diabetes mellitus type 2 patients.

An animal study using mice found that American ginseng lowers elevated blood sugar levels and reduces body weight in an animal model of diabetes mellitus type 2.

Libido (men):

A study conducted on rats found that American ginseng increases the number of sexual encounters initiated by males (indicating increased libido).  This effect may occur from American ginseng influencing the body’s ability to produce dopamine, probably by reducing prolactin levels.  High prolactin levels are known to reduce sexual desire.

Dosage:

500 – 1,500 mg per day (using unstandardized American ginseng products).

400 - 800 mg per day for American ginseng products that have been standardized to contain 10.28% Ginsenosides.

References

ADD (Attention Deficit Disorder_

· Lyon, M. R., et al.  Effect of the herbal extract combination Panax quinquefolium and Ginkgo biloba on attention-deficit hyperactivity disorder: a pilot study.  J Psychiatry Neurosci.  26:221-228, 2001.

Alzheimer’s Disease

· Lewis, R., et al.  Non-ginsenoside nicotinic activity in ginseng species.  Phytother Res.  13(1):59-64, 1999.

Diabetes Type 2

· Vuksan, V., et al.  American ginseng (Panax quinquefolius L) reduces postprandial glycemia in nondiabetic subjects and subjects with type 2 diabetes mellitus.  Arch Intern Med.  160(7):1009-1013, 2000.

Libido (men)

· Murphy, L. L., et al.  Effect of American ginseng (Panax quinquefolium) on male copulatory behavior in the rat.  Physiol Behav.  15;64(4):445-50, 1998.

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